Localization and characterization of the human ADP-ribosylation factor 5 (ARF5) gene
RE McGuire, SP Daiger, ED Green - Genomics, 1997 - Elsevier
ADP-ribosylation factor 5 (ARF5) is a member of the ARF gene family. The ARF proteins
stimulate thein vitroADP-ribosyltransferase activity of cholera toxin and appear to play a role
in vesicular traffickingin vivo. We have mapped ARF5, one of the six known mammalian ARF
genes, to a well-defined yeast artificial chromosome contig on human chromosome 7q31. 3.
In addition, we have isolated and sequenced an∼ 3.2-kb genomic segment that contains
the entire ARF5 coding region, revealing the complete intron–exon structure of the gene …
stimulate thein vitroADP-ribosyltransferase activity of cholera toxin and appear to play a role
in vesicular traffickingin vivo. We have mapped ARF5, one of the six known mammalian ARF
genes, to a well-defined yeast artificial chromosome contig on human chromosome 7q31. 3.
In addition, we have isolated and sequenced an∼ 3.2-kb genomic segment that contains
the entire ARF5 coding region, revealing the complete intron–exon structure of the gene …
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